Molecular BiologybioRxivPreprint
A phenotypic screen identified KEAP1-kelch domain blockade as a mechanism to restore cardiac function in the setting of chronic severe hemodynamic stress
John J. Upson, Christine G. Schnackenberg, Brian G. Lawhorn…·John R. Toomey
A gene expression-based screen in iPSC-CMs identified KEAP1-kelch domain blockers as effective in restoring cardiac function under chronic hemodynamic stress.
DOI 10.1101/2025.09.24.678104