Preclinical evaluation of ixazomib for high-risk pediatric brain tumors
Elizabeth Janko, Faye M. Walker, Mathew Slade, Etienne P. Danis, Pradeep Bompada, Lays Martin Sobral, Julia Chapman, Ishmeen Kaur, Simran Bal, Gabrielle Link, Nicholas McQuillan, Jean M. Mulcahy Levy, Adam L. Green, Nathan A. Dahl
This study evaluates ixazomib's efficacy against high-risk pediatric brain tumors, finding it cytotoxic but with limited CNS penetration.
bioRxiv · Sep 18, 2026 · PreprintCancer Biology