Author

Krishna P.C. Madhavan

Children's Hospital ColoradoORCID 0000-0002-1234-413XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Angela M. PierceiD· 2 shared Etienne P. DanisiD· 2 shared Faye M. WalkeriD· 2 shared Ilango BalakrishnaniD· 2 shared Nathan A. DahliD· 2 shared Rajeev VibhakariD· 2 shared Sujatha VenkataramaniD· 2 shared Adam L. GreeniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Angela M. PierceORCID

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2 papers

Recent·Most cited

Targeting Diffuse Midline Glioma with a novel anti-CD99 Antibody

Ilango Balakrishnan, Krishna P.C. Madhavan, Angela M. Pierce, Joshua Michlin, Breauna Brunt, Senthilnath Lakshmanachetty, Dong Wang, John A. DeSisto, Zachary James Nuss, Nathan L. Davidson, Faye M. Walker, Ammu Suresh, Andrew M. Donson, Bridget L. Sanford, Kenneth L. Jones, , Sujatha Venkataraman

This paper identifies CD99 as a therapeutic target in K27M+DMGs, showing that a novel anti-CD99 antibody reduces tumor growth and enhances radiation efficacy in preclinical models.

Cancer Research · May 27, 2025Peer-reviewedCancer Biology

Targeting processive transcription for Myc-driven circuitry in medulloblastoma

Lays Martin Sobral, Faye M. Walker, Krishna P.C. Madhavan, Elizabeth Janko, Sahiti Donthula, Etienne P. Danis, Pradeep Bompada, Ilango Balakrishnan, Dong Wang, Angela M. Pierce, Mary M. Haag, Billie J. Carstens, Natalie Julie Serkova, Nicholas K. Foreman, Sujatha Venkataraman, , Nathan A. Dahl

This study identifies CDK9 as a conserved dependency in Myc-driven medulloblastoma and shows that CDK9 inhibition disrupts Myc-driven transcriptional programs, leading to anti-tumor effects.

Neuro-Oncology · May 12, 2025Peer-reviewedCancer Biology