A genetically defined injured C-fibre nociceptor associated with neuromasdrives chronic spontaneous neuropathic pain
Xiangsunze Zeng, Rosa I. Martinez-Garcia, Shamsuddin A. Bhuiyan, Keunjung Heo, Natalie MacKinnon-Booth, Elke Bentley, Emily K. Shea, Kangling Wu, Omer Barkai, Bruna Lenfers Turnes, Selwyn S. Jayakar, Bárbara Gómez-Eslava, Mustafa Qadir Hameed, Celine Santiago, Karina Lezgiyeva, , Clifford J. Woolf
The paper identifies a specific subtype of injured C-fibre nociceptors in neuromas that drive chronic spontaneous neuropathic pain in mice.
bioRxiv · Sep 30, 2025 · PreprintNeuroscience