Omer Barkai

This study identifies neurotensin-expressing neurons in the parabrachial nucleus that modulate colonic sensitivity and pain in colitis, suggesting neurotensin as a therapeutic target.

The paper identifies a specific subtype of injured C-fibre nociceptors in neuromas that drive chronic spontaneous neuropathic pain in mice.

This paper uses machine learning to detect early cervical instability in ALS mice, identifying it as a behavioral biomarker for early disease detection.

ARBEL automatically classifies 3D pain behaviors in mice using light-based analysis and pose estimation, achieving high precision and enabling efficient drug screening.

The paper demonstrates that efferent signaling along nociceptive terminals increases during inflammation, leading to enhanced calcium signaling and mediator release in remote terminals.

This study demonstrates the use of lipid nanoparticles to deliver siRNA to dorsal root ganglion neurons, effectively silencing TRPV1 and reducing pain-related behaviors.

The paper investigates how spinal cord networks in mice encode inflammatory hyperalgesia through changes in neuronal activity and synaptic inhibition.

The paper shows that the input-output relation of primary nociceptive neurons depends on the morphology of their peripheral terminals and how multiple terminals integrate noxious stimuli.