Author

Ellen Grünewald

Institute of Genetics and Cancer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Andrew Mark McIntoshiD· 2 shared Douglas BlackwoodiD· 2 shared J. Kirsty Millar· 2 shared Karen Burr· 2 shared Kyriakos D. EconomidesiD· 2 shared Mandy JohnstoneiD· 2 shared Siddharthan ChandraniD· 2 shared Stephen M. LawrieiD· 2 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersNeuroscience

Andrew Mark McIntoshORCID

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2 papers

Recent·Most cited

Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction

Navneet A. Vasistha, Mandy Johnstone, Samantha K. Barton, Steffen E. Mayerl, Bhuvaneish Thangaraj Selvaraj, Pippa A. Thomson, Owen Dando, Ellen Grünewald, Clara Alloza, Mark E. Bastin, Matthew R. Livesey, Kyriakos D. Economides, Dario Magnani, Paraskevi Makedonopolou, Karen Burr, , Siddharthan Chandran

The paper investigates the impact of a t(1;11) translocation on white matter integrity and oligodendrocyte-myelin function using DTI and cellular models.

Molecular Psychiatry · Sep 3, 2019Peer-reviewedNeuroscience

DISC1 regulates N-Methyl-D-Aspartate receptor dynamics: Abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

Elise L.V. Malavasi, Kyriakos D. Economides, Ellen Grünewald, Paraskevi Makedonopoulou, Philippe Emmanuel Gautier, Shaun Mackie, Laura C. Murphy, Hannah Murdoch, Darragh Crummie, Fumiaki Ogawa, Daniel L. McCartney, Shane T. O’Sullivan, Karen Burr, Helen Scott Torrance, Jonathan Phillips, , J. Kirsty Millar

This study shows that a DISC1 mutation linked to mental illness disrupts NMDAR dynamics and synaptic function in neurons, affecting excitatory synapses and vesicle dynamics.

Translational Psychiatry · Sep 6, 2018Peer-reviewedNeuroscience