Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites
Damilola C. Lawore, Smrutiti Jena, Alicia R. Berard, Kenzie Birse, Alana Lamont, Romel D. Mackelprang, Laura Noël‐Romas, Michelle Perner, Xuanlin Hou, Elizabeth Irungu, Nelly Mugo, Samantha Knodel, Timothy R. Muwonge, Elly Katabira, Sean M. Hughes, , Douglas K. Brubaker
The paper develops a systems biology framework called the Pharmacobiome to analyze the anti-cancer potential of vaginal microbes and metabolites by comparing their effects on host gene expression to known drugs.
Frontiers in Microbiology · Sep 16, 2025Peer-reviewedSystems Biology