Author

Emily Days

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:electrophysiology· 1 Assay:structural biology· 1

Frequent Co-Authors

Joshua A. BaueriD· 2 shared Abhishek A. ChakrabortyiD· 1 shared Alex G. WatersoniD· 1 shared Alexander EarsleyiD· 1 shared Alfred L. GeorgeiD· 1 shared Ana Cristina Chang-GonzaleziD· 1 shared Biao QiuiD· 1 shared Carleigh Salem· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Joshua A. BauerORCID

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2 papers

Recent·Most cited

High Throughput Screening Identifies a Small Molecule Trafficking Corrector for Long-QT Syndrome Associated KCNQ1 Variants

Katherine R. Clowes, Carlos G. Vanoye, Ana Cristina Chang-Gonzalez, Ian M. Romaine, Katherine M. Stefanski, Mason C. Wilkinson, Joshua A. Bauer, Thomas P. Hasaka, Emily Days, Reshma Desai, Kathryn R. Butcher, Gary A. Sulikowksi, Alex G. Waterson, Jens Meiler, Kaitlyn V. Ledwitch, , Charles R. Sanders

This study identifies a small molecule, VU0494372, that enhances KCNQ1 expression and trafficking, offering a potential therapeutic approach for LQTS.

bioRxiv · Oct 13, 2025 · PreprintBiochemistry

Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer

Pooneh Koochaki, Biao Qiu, Jesse A. Coker, Alexander Earsley, Nancy S. Wang, Todd Romigh, Christopher M. Goins, Carleigh Salem, Dehui Mi, Emily Days, Joshua A. Bauer, Shaun R. Stauffer, Olga Boudker, Abhishek A. Chakraborty

This study determines the cryo-EM structure of SLC1A1 bound to an inhibitor, identifies its binding mechanism, and develops improved inhibitors with enhanced cytotoxicity in kidney cancer cells.

bioRxiv · Jul 3, 2025 · PreprintCancer Biology