BioengineeringPLoS ONEPeer-reviewed
Leveraging a synthetic biology approach to enhance BCG-mediated expansion of Vγ9Vδ2 T cells
Christine M. Qabar, Allison W. Roberts, Lucas M. Waldburger…·Jeffery S. Cox
This paper uses synthetic biology to engineer BCG to produce HMBPP, enhancing Vγ9Vδ2 T cell expansion without feedback inhibition, offering a strategy to improve TB vaccine efficacy.
2 citations