Author

Dan A. Portnoy

University of California, Berkeley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Jeffery S. CoxiD· 2 shared Alex Choi· 1 shared Allison W. RobertsiD· 1 shared Bennett H. Penn· 1 shared Chen Chen· 1 shared Christine M. QabariD· 1 shared Cyrus Maher· 1 shared Edward E. K. BaidooiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

Jeffery S. CoxORCID

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2 papers

Recent·Most cited

Leveraging a synthetic biology approach to enhance BCG-mediated expansion of Vγ9Vδ2 T cells

Christine M. Qabar, Allison W. Roberts, Lucas M. Waldburger, Edward E. K. Baidoo, Emine Akyuz Turumtay, Jay D. Keasling, Dan A. Portnoy, Jeffery S. Cox

This paper uses synthetic biology to engineer BCG to produce HMBPP, enhancing Vγ9Vδ2 T cell expansion without feedback inhibition, offering a strategy to improve TB vaccine efficacy.

PLoS ONE · Apr 6, 2026Peer-reviewedBioengineering

An Mtb-Human Protein-Protein Interaction Map Reveals that Bacterial LpqN Antagonizes CBL, a Host Ubiquitin Ligase that Regulates the Balance Between Anti-Viral and Anti-Bacterial Responses

Bennett H. Penn, Zoe Netter, Jeffrey R. Johnson, John Von Dollen, Gwendolyn M. Jang, Tasha Johnson, Yamini M. Ohol, Cyrus Maher, Samantha L. Bell, Kristina Geiger, Xiaotang Du, Alex Choi, Trevor Parry, Mayumi Naramura, Chen Chen, , Nevan J. Krogan

The paper identifies Mtb-human protein-protein interactions, showing LpqN antagonizes CBL, a host ubiquitin ligase that balances anti-viral and anti-bacterial responses in macrophages.

bioRxiv · Oct 17, 2017 · PreprintMicrobiology