The epigenetic regulator TRIM24 controls melanoma cell dedifferentiation and resistance to treatment in melanoma
Simon Durand, Félix Boivin, Roxane M. Pommier, Laetitia Barbollat‐Boutrand, Maxime Grimont, Félix Pham, Marion Dufeu, Eric Cumunel, Raphaël Schneider, Anthony Ferrari, Anaïs Eberhardt, Stéphane Dalle, Julie Caramel
This study identifies TRIM24 as an epigenetic regulator that promotes melanoma cell dedifferentiation and treatment resistance, with potential as a druggable target.
bioRxiv · May 20, 2025 · PreprintCancer Biology