Hierarchical Gating of Cortical Population Dynamics Drives Pain
Eric Hu, Guanghao Sun, Elaine Zhu, Chengju Tian, Isabel Reyes, Zhe Sage Chen, Qiaosheng Zhang, Jing Wang
This study identifies a hierarchical cortical circuit involving the prelimbic and anterior cingulate cortex that modulates pain behavior through synaptic, cellular, and network-level mechanisms.
bioRxiv · Mar 10, 2026 · PreprintNeuroscience