Cancer BiologyBreast Cancer ResearchPeer-reviewed
Atypical Cell Cycle Regulation Promotes Mammary Stem Cell Expansion and Therapeutic Resistance
Bre‐Anne Fifield, John Vusich, Erika Haberfellner…·Lisa Ann Porter
This study shows Spy1 promotes mammary stem cell expansion and therapy resistance by overriding cell cycle checkpoints, especially in combination with p53 loss, leading to more aggressive breast cancers.
2 citations