John Vusich

This study identifies tumor-derived FXII as a driver of liver metastasis in breast cancer by engaging the intrinsic coagulation cascade, with anti-coagulation reducing metastasis in a mouse model.

This study shows E2F5 promotes differentiation of luminal progenitors into alveolar precursors during early pregnancy, coordinating proliferation and differentiation in mammary development.

This study shows Spy1 promotes mammary stem cell expansion and therapy resistance by overriding cell cycle checkpoints, especially in combination with p53 loss, leading to more aggressive breast cancers.