CRISPR-activation reveals key resistance genes and vulnerabilities of copy number variants in Candida albicans
Pétra Vande Zande, Nicholas C Gervais, Erika Renee Schell, Piper Zajac, Katura Metzner, Rebecca S. Shapiro, Anna M. Selmecki
This study uses CRISPR-activation to identify genes with fitness effects in Candida albicans isolates, revealing resistance genes and vulnerabilities associated with copy number variants.
bioRxiv · Aug 9, 2026 · PreprintMicrobiology