Katura Metzner

This study uses CRISPR-activation to identify genes with fitness effects in Candida albicans isolates, revealing resistance genes and vulnerabilities associated with copy number variants.

This study shows that micafungin exposure selects for multidrug resistance in C. lusitaniae through mutations in ERG3, leading to sterol reprogramming and cell wall remodeling.

This study shows how azole resistance in Candida albicans evolves through copy number variation followed by KSR1 loss of heterozygosity, resulting in a >500-fold resistance increase.