Author
HudsonAlpha Institute for BiotechnologyORCID 0000-0002-3708-4805Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Rebecca M. Hauser, Henry L. Limbo, J. Nicholas Brazell…·J. Nicholas Cochran
The paper identifies cis-regulatory elements and genetic variation effects in the MAPT locus using MPRA and CRISPRi in neuronal and HEK293FT cells.
Ashlyn G. Anderson, Brianne B. Rogers, Erin A. Barinaga…·J. Nicholas Cochran
The paper identifies cell type-specific regulatory elements in nine mammals and shows their conservation and association with neuropsychiatric and neurodegenerative disease risks.
Iván Rodríguez-Nunez, Samuel C. Bartley, Jared W. Taylor…·R Myers
The paper introduces a standardized iPSC-derived microglia model to study transcriptional regulatory networks in CNS diseases and identifies disease-associated genetic variants.
Brianne B. Rogers, Ashlyn G. Anderson, Shelby N. Lauzon…·J. Nicholas Cochran
The paper identifies cis-regulatory elements (cCREs) controlling MAPT expression and links genetic variation in these elements to Alzheimer's disease risk.
Susan M. Hiatt, James M.J. Lawlor, Lori H. Handley…·Gregory M. Cooper
This paper uses long-read genome sequencing to identify pathogenic variants in neurodevelopmental disorders, finding clinically relevant structural variants in two of six probands.