B cell responses specific for polyomavirus-derived oncoprotein are predictive of Merkel cell carcinoma tumor control
Haroldo J. Rodriguez, Allison Jeanne Remington, Matthew D. Gray, Rian Alam, Macy W. Gilmour, Carina Morningstar, Gabriel F. Alencar, Thomas Pulliam, Erin McClure, Neha Singh, Francesca Urselli, Katrina Poljakov, Kimberly S. Smythe, Rima M. Kulikauskas, Kristin L. Robinson, , Justin J. Taylor
The paper shows that B cells specific for viral oncoproteins in Merkel cell carcinoma tumors predict long-term disease control and enhance T cell responses.
bioRxiv · Jul 22, 2025 · PreprintImmunology