Ata S. Moshiri

This study shows human CD4 T cells can drive antitumor immunity in MHC class II-negative cancers through indirect antigen presentation via APCs.

This study shows that lymph nodes actively drive melanoma evolution and immune evasion, linking regional metastasis to poor patient outcomes.

This study shows that chromatin architecture and physical constriction together drive phenotype switching and metastasis in melanoma by altering CTCF positioning and heterochromatin structure.

This study identifies HOXD13 as a driver of a developmental program in melanoma that promotes angiogenesis and suppresses T-cell infiltration through a gene regulatory axis involving VEGFA, SEMA3A, and CD73.

This study shows that IFNγ suppresses lymphatic vessel growth and metastasis by altering metabolism and immune function in melanoma.

The paper shows that B cells specific for viral oncoproteins in Merkel cell carcinoma tumors predict long-term disease control and enhance T cell responses.