Estanislao Daniel De La Cruz

This paper introduces a new optical framework and imaging devices that enable scalable, high-resolution, multi-immersion light-sheet microscopy for biological samples.

This study demonstrates that dissociated hippocampal cells can self-organize into network dynamics similar to in vivo cognitive cell assemblies, showing resilience and response to perturbations.

This paper introduces a cost-effective, scalable light sheet microscopy framework for high-resolution imaging of living and cleared samples, demonstrating its application on various biological samples.

This study uses whole-brain mapping to show that chronic ketamine exposure reduces dopamine neurons in midbrain regions but increases them in the hypothalamus, with divergent effects on brain connectivity.

This paper introduces ctASLM, a light-sheet microscopy technique with sub-micron isotropic resolution and large-scale imaging, enabling automated cell and subcellular feature detection in cleared tissues.