Author

Pauline Affatato

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Maria Antonietta ToschesiD· 2 shared Akihiro ItoigawaiD· 1 shared Alonso Ortega GurrolaiD· 1 shared Astrid DeryckereiD· 1 shared Atsuko YamaguchiiD· 1 shared Atsuko YamashitaiD· 1 shared Benjamin W. HaydockiD· 1 shared Borja RehiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioengineering

Maria Antonietta ToschesORCID

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Author profile →

3 papers

Recent·Most cited

Early origin of sugar sensing in jawed vertebrates

Qiaoyi Liang, Yasuka Toda, Pauline Affatato, Gentoku Kakizaki, Hitomi Kaname, Kayoko Suzuki, Tae Kuramoto, Meng‐Ching Ko, Maxime Policarpo, Julia F. Cramer, Akihiro Itoigawa, Keisuke Furumitsu, Keren R. Sadanandan, Shigehiro Kuraku, Atsuko Yamaguchi, , Maude W. Baldwin

This study investigates the evolutionary origin of sugar sensing in vertebrates, finding that it predates angiosperms and involves multiple independent T1R-based mechanisms.

bioRxiv · Aug 28, 2026 · PreprintEvolutionary Biology

Hybrid Solid-Liquid Optics Enable Scalable, High-Resolution, Multi-Immersion Light-Sheet Microscopy

Cheng Gong, Pauline Affatato, Matt Fay, Sudha R. Guttikonda, Nathan O’Connor, Emerson Noble, Maci Heal, Benjamin W. Haydock, Renee Mapa, Estanislao Daniel De La Cruz, Giacomo Gattoni, Johanna E. Kowalko, Maria Antonietta Tosches, Charles R. Gerfen, René Hen, , Raju Tomer

This paper introduces a new optical framework and imaging devices that enable scalable, high-resolution, multi-immersion light-sheet microscopy for biological samples.

Nature Biotechnology · Jun 9, 2026Peer-reviewedBioengineering

A conserved logic for the development of cortical layering in tetrapods

Astrid Deryckere, Saket Choudhary, Connor Lynch, Lian Kirit Limperis, Pauline Affatato, Jamie Woych, Elias Gumnit, Alonso Ortega Gurrola, Rahul Satija, Christian Mayer, Maria Antonietta Tosches

The paper shows that cortical layering in tetrapods follows conserved developmental principles, with mammals displaying an inverted layer order.

bioRxiv · Oct 1, 2025 · PreprintDevelopmental Biology