Synergistic Notch-WNT Activation Underlies Pediatric Dilated Cardiomyopathy
Obed Ofori Nyarko, Ethan Rausch, Jared R.H. Goff, Anis Karimpour‐Fard, Caitlyn S. Conard, Laura Hernandez‐Lagunas, McKenna P.A. Burns, Michael R. Bristow, Joseph C. Cleveland, Matthew L. Stone, Brisa Peña, Shelley D. Miyamoto, Brian L. Stauffer, Carmen C. Sucharov
This study identifies synergistic Notch-WNT signaling activation in pediatric dilated cardiomyopathy and shows its inhibition improves cardiac function.
bioRxiv · Jun 7, 2025 · PreprintMolecular Biology