Carmen C. Sucharov

This study compares mitochondrial and cardiolipin changes in pediatric and adult failing hearts before and after VAD support, finding age-related differences in cardiolipin remodeling and mitochondrial function.

This study identifies circulating miRNA and protein signatures that predict clinical outcomes in pediatric dilated cardiomyopathy with high discriminatory accuracy.

This study identifies the pericardium's origin from anterior mesothelial progenitors in zebrafish, distinct from the heart field, and links pericardial stiffness to pediatric cardiomyopathies.

This study identifies synergistic Notch-WNT signaling activation in pediatric dilated cardiomyopathy and shows its inhibition improves cardiac function.

This study shows that fetal serum from obese pregnant women induces pathological cardiomyocyte hypertrophy in neonatal rats through circulating factors.

This study investigates how serum factors and PDE5 inhibitor therapy affect cardiomyocyte metabolism in single ventricle heart disease, finding that PDE5 inhibitors improve mitochondrial function and metabolic intermediates.