Shelley D. Miyamoto

Mitochondrial and Cardiolipin Adaptations to Ventricular Assist Device Support in Pediatric Versus Adult Failing Myocardium

This study compares mitochondrial and cardiolipin changes in pediatric and adult failing hearts before and after VAD support, finding age-related differences in cardiolipin remodeling and mitochondrial function.

Circulating miRNA-Protein Signatures Predict Outcomes in Pediatric Dilated Cardiomyopathy

This study identifies circulating miRNA and protein signatures that predict clinical outcomes in pediatric dilated cardiomyopathy with high discriminatory accuracy.

Synergistic Notch-WNT Activation Underlies Pediatric Dilated Cardiomyopathy

This study identifies synergistic Notch-WNT signaling activation in pediatric dilated cardiomyopathy and shows its inhibition improves cardiac function.

Impact of Serum Circulating Factors and PDE5 Inhibitor Therapy on Cardiomyocyte Metabolism in Single Ventricle Heart Disease

This study investigates how serum factors and PDE5 inhibitor therapy affect cardiomyocyte metabolism in single ventricle heart disease, finding that PDE5 inhibitors improve mitochondrial function and metabolic intermediates.