Heterozygosity for Crohn's Disease Risk Allele of ATG16L1 Protects against Bacterial Infection
Xiaomin Yao, Eugene Rudensky, Patricia K. Martin, Brittany M. Miller, Isabel Vargas, Erin E. Zwack, Keenan A. Lacey, Zhengxiang He, Gláucia C. Furtado, Sérgio A. Lira, Victor J. Torres, Bo Shopsin, Ken Cadwell
The paper shows that heterozygosity for the ATG16L1 T300A allele protects against Salmonella infection, while homozygosity increases susceptibility.
Immunity · Feb 25, 2024Peer-reviewedImmunology