Author

Keenan A. Lacey

New York UniversityORCID 0000-0002-9242-0170Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Bo ShopsiniD· 2 shared Erin E. ZwackiD· 2 shared Victor J. TorresiD· 2 shared Alejandro PirontiiD· 1 shared Brittany M. MilleriD· 1 shared Chunyi ZhouiD· 1 shared Daiane BoffiD· 1 shared Eugene Rudensky· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Bo ShopsinORCID

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Author profile →

2 papers

Recent·Most cited

Prophage-encoded methyltransferase drives adaptation of community-acquired methicillin-resistant Staphylococcus aureus

Robert J. Ulrich, Magdalena M Podkowik, Rebecca Tierce, Irnov Irnov, Gregory Putzel, Nora M. Samhadaneh, Keenan A. Lacey, Daiane Boff, Sabrina M. Morales, Sohei Makita, Theodora K. Karagounis, Erin E. Zwack, Chunyi Zhou, Randie H. Kim, Karl Drlica, , Bo Shopsin

This study identifies a prophage-encoded methyltransferase, pamA, that enhances virulence in CA-MRSA by epigenetically upregulating fnbA, promoting biofilm formation and abscess size.

Journal of Clinical Investigation · Jul 22, 2025Peer-reviewedMicrobiology

Heterozygosity for Crohn's Disease Risk Allele of ATG16L1 Protects against Bacterial Infection

Xiaomin Yao, Eugene Rudensky, Patricia K. Martin, Brittany M. Miller, Isabel Vargas, Erin E. Zwack, Keenan A. Lacey, Zhengxiang He, Gláucia C. Furtado, Sérgio A. Lira, Victor J. Torres, Bo Shopsin, Ken Cadwell

The paper shows that heterozygosity for the ATG16L1 T300A allele protects against Salmonella infection, while homozygosity increases susceptibility.

Immunity · Feb 25, 2024Peer-reviewedImmunology