The p48 isoform of the PA2G4/EBP1/ITAF45 oncoprotein is required for the encephalomyocarditis virus IRES-driven translation initiation
Artem S. Kushchenko, Violetta A Golovko, Eugenia A. Panova, Anastasia P. Sukhinina, Ekaterina E Gladneva, Alexandr Y. Krasota, Yury Y. Ivin, Anastasia V Poteryakhina, Vadim I. Agol, Sergey E. Dmitriev
The paper identifies the p48 isoform of ITAF45 as essential for EMCV and Mengovirus replication, showing isoform-specific roles in IRES-driven translation.
Nucleic Acids Research · Oct 29, 2025Peer-reviewedMolecular Biology