Author

Igor A. Ivanov

Russian Academy of SciencesORCID 0000-0001-6785-4420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Anastasia N. Zolotar· 3 shared Denis A. KleymenoviD· 3 shared Denis Y. LogunoviD· 3 shared Elena P. MazuninaiD· 3 shared Evgeniia N. BykoniaiD· 3 shared Evgeny V. UsacheviD· 3 shared Sergey E. DmitrieviD· 3 shared Vladimir A. GushchiniD· 3 shared

Activity by Year

2023-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Anastasia N. Zolotar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivDec 30, 2023

Major role of S-glycoprotein in providing immunogenicity and protective immunity in mRNA lipid nanoparticle vaccines based on SARS-CoV-2 structural proteins

Evgeniia N. Bykonia, Denis A. Kleymenov, Vladimir A. Gushchin…·Alexander L. Gintsburg

This study evaluates mRNA-LNP vaccines encoding SARS-CoV-2 structural proteins, finding that the S protein enhances immune responses to N protein, while M protein has low immunogenicity.

DOI 10.3390/vaccines12040379

mousebulk RNA-seq

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ImmunologybioRxivDec 30, 2023

Trivalent mRNA vaccine-candidate against seasonal flu with cross-specific humoral immune response

Elena P. Mazunina, Vladimir A. Gushchin, Denis A. Kleymenov…·Alexander L. Gintsburg

This study develops a trivalent mRNA vaccine candidate for seasonal flu, showing higher immunogenicity and cross-specific humoral immune response compared to an inactivated split vaccine.

DOI 10.3389/fimmu.2024.1381508

experimental assaydrug response / drug discovery

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Molecular BiologyFrontiers in ImmunologyPeer-reviewedFeb 14, 2023

Single-domain antibody delivery using an mRNA platform protects against lethal doses of botulinum neurotoxin A

Eugenia A. Panova, Denis A. Kleymenov, Dmitry V. Shcheblyakov…·Gintsburg Al

This paper develops an mRNA platform for delivering single-domain antibodies, achieving 100% protection against high doses of botulinum neurotoxin A in mice.

34 citationstop 3%

mouseexperimental assay

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Synthetic BiologyNucleic Acids ResearchPeer-reviewedFeb 4, 2023

Red light-emitting short Mango-based system enables tracking a mycobacterial small noncoding RNA in infected macrophages

Oksana S. Bychenko, Alexei A Khrulev, Julia I. Svetlova…·Andrey V. Aralov

10 citations

experimental assay

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