Dietary fibre reverses adverse post-stroke outcomes in mice via short-chain fatty acids and its sensing receptors GPR41, GPR43 and GPR109A
Alex Peh, Evany Dinakis, Hamdi A. Jama, Dovile Anderson, Darren J. Creek, Gang Zheng, Michael de Veer, Charles Reay Mackay, Tenghao Zheng, Barbara K. Kemp‐Harper, Brad R. S. Broughton, Francine Z. Marques
This study shows that dietary fibre and SCFA supplementation improve post-stroke outcomes in mice by modulating the gut microbiome and acting through GPR41/43/109A receptors.
bioRxiv · May 15, 2023 · PreprintNeuroscience