Author

Charles Reay Mackay

Qilu University of TechnologyORCID 0000-0002-6338-7340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 1

Frequent Co-Authors

Alex PehiD· 2 shared Darren J. CreekiD· 2 shared Dovile AndersoniD· 2 shared Evany Dinakis· 2 shared Francine Z. MarquesiD· 2 shared Hamdi A. Jama· 2 shared Barbara K. Kemp‐HarperiD· 1 shared Brad R. S. BroughtoniD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Alex PehORCID

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2 papers

Recent·Most cited

Dietary fibre reverses adverse post-stroke outcomes in mice via short-chain fatty acids and its sensing receptors GPR41, GPR43 and GPR109A

Alex Peh, Evany Dinakis, Hamdi A. Jama, Dovile Anderson, Darren J. Creek, Gang Zheng, Michael de Veer, Charles Reay Mackay, Tenghao Zheng, Barbara K. Kemp‐Harper, Brad R. S. Broughton, Francine Z. Marques

This study shows that dietary fibre and SCFA supplementation improve post-stroke outcomes in mice by modulating the gut microbiome and acting through GPR41/43/109A receptors.

bioRxiv · May 15, 2023 · PreprintNeuroscience

Dietary fibre controls blood pressure and cardiovascular risk by lowering large intestinal pH and activating the proton-sensing receptor GPR65

Liang Xie, Rikeish R. Muralitharan, Evany Dinakis, Simona Antonacci, Kwan Charmaine Leung, Zoe McArdle, Katrina Mirabito Colafella, Michael E. Nakai, Madeleine R. Paterson, Alex Peh, Hamdi A. Jama, Ekaterina Salimova, Dovile Anderson, Caroline Ang, Jahangir Alam, , Francine Z. Marques

This study shows dietary fiber lowers blood pressure by reducing large intestinal pH and activating GPR65 in CD8+ T cells, which reduces inflammation and hypertension-related damage.

bioRxiv · Nov 17, 2022 · PreprintMolecular Biology