Author

Jahangir Alam

Duke UniversityORCID 0000-0002-7935-6346Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Aaron Cook· 1 shared Advaiti Pai KaneiD· 1 shared Alamgir Hossain· 1 shared Alex PehiD· 1 shared Barton F. HaynesiD· 1 shared Bhishem Thakur· 1 shared Caroline AngiD· 1 shared Charles Reay MackayiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Aaron Cook

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Anti-HIV-1 B cell antigen receptor signaling and structure

Bhishem Thakur, Jahangir Alam, Kenneth D. Cronin, Parth Patel, Kara M. Anasti, Advaiti Pai Kane, Alamgir Hossain, Hung Nguyen Do, Katayoun Mansouri, Taylor N. Spence, Robert J. Edwards, Rasangi Pathirage, Katarzyna Janowska, Muralikrishna Lella, Aaron Cook, , S. Munir Alam

This study reports cryo-EM structures of full-length BCRs, revealing their dynamic conformation and antigen binding-induced signaling mechanisms.

iScience · Nov 1, 2026Peer-reviewedImmunology

Dietary fibre controls blood pressure and cardiovascular risk by lowering large intestinal pH and activating the proton-sensing receptor GPR65

Liang Xie, Rikeish R. Muralitharan, Evany Dinakis, Simona Antonacci, Kwan Charmaine Leung, Zoe McArdle, Katrina Mirabito Colafella, Michael E. Nakai, Madeleine R. Paterson, Alex Peh, Hamdi A. Jama, Ekaterina Salimova, Dovile Anderson, Caroline Ang, Jahangir Alam, , Francine Z. Marques

This study shows dietary fiber lowers blood pressure by reducing large intestinal pH and activating GPR65 in CD8+ T cells, which reduces inflammation and hypertension-related damage.

bioRxiv · Nov 17, 2022 · PreprintMolecular Biology