A novel Fis1 inhibiting peptide reverses diabetic endothelial dysfunction in human resistance arteries
K. A. Nolden, M. Kakarla, J. M. Egner, J. Wang, M. C. Harwig, V. K. Puppala, B. C. Hofeld, L. A. Arnold, D. Z. Trykall, F. C. Peterson, M. L. Roberts, D. M. Jensen, R. B. Hill, M. E. Widlansky
This study shows that inhibiting Fis1 improves endothelial function in diabetic vessels by enhancing NO availability and reducing mitochondrial ROS.
bioRxiv · Nov 16, 2020 · PreprintPhysiology