Author

F. Granucci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Protti· 2 shared N. Clementi· 2 shared N. Mancini· 2 shared R. Spreafico· 2 shared A. Biondi· 1 shared A. Broggi· 1 shared A. Diaz Basabe· 1 shared A. Lo Cascio· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

G. Protti

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tumor infiltrating iNKT cells sustain neutrophil pro-tumorigenic functions influencing disease progression in human colorectal cancer

G. Lattanzi, F. Strati, A. Diaz Basabe, F. Perillo, C. Amoroso, G. Protti, M. R. Giuffre, L. Baldari, E. Cassinotti, M. Ghidini, B. Galassi, G. Lopez, D. Noviello, L. Porretti, E. Trombetta, , F. Facciotti

The paper shows tumor-infiltrating iNKT cells have pro-tumorigenic effects in CRC by promoting neutrophil functions and poor patient outcomes.

bioRxiv · Oct 19, 2022 · PreprintImmunology

Maturation signatures of conventional dendritic cell subtypes in COVID-19 reflect direct viral sensing

L. Marongiu, G. Protti, F. A. Facchini, M. Valache, F. Mingozzi, V. Ranzani, A. R. Putignano, L. Salviati, V. Bevilacqua, S. Curti, M. Crosti, M. D'Angio, L. R. Bettini, A. Biondi, L. Nespoli, , F. Granucci

This study identifies maturation signatures of conventional dendritic cell subtypes in COVID-19, showing that cDC2s exhibit viral sensing and inflammatory activation while losing antigen presentation capacity, correlating with disease severity.

bioRxiv · Mar 3, 2021Immunology

Type III interferons disrupt the lung epithelial barrier upon viral recognition.

A. Broggi, S. Ghosh, B. Sposito, R. Spreafico, F. Balzarini, A. Lo Cascio, N. Clementi, M. De Santis, N. Mancini, F. Granucci, I. Zanoni

This study shows that type III interferons from lung dendritic cells damage the epithelial barrier and increase susceptibility to bacterial infections during viral recognition.

bioRxiv · May 5, 2020Immunology