Author

L. Marongiu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

I. Zanoni· 2 shared N. Clementi· 2 shared N. Mancini· 2 shared R. Spreafico· 2 shared A. Ambrosi· 1 shared A. Biondi· 1 shared A. Bottazzi· 1 shared A. Broggi· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

I. Zanoni

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of viral dose and administration time in simulated phage therapy occurrences

S. Plunder, T. Helling, S. Venturelli, L. Marongiu

This study uses machine learning to determine optimal viral dose and administration time for effective phage therapy in simulated microbial consortia.

bioRxiv · May 5, 2022 · PreprintMicrobiology

Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.

B. Sposito, A. Broggi, L. Pandolfi, S. Crotta, R. Ferrarese, S. Sisti, N. Clementi, A. Ambrosi, E. Liu, V. Frangipane, L. Saracino, L. Marongiu, F. Facchini, A. Bottazzi, T. Fossali, , I. Zanoni

This study examines IFN-I and IFN-III expression patterns in the respiratory tract of COVID-19 patients, finding higher IFN-III levels in severe cases and varying roles across anatomical sites.

bioRxiv · Mar 30, 2021 · PreprintImmunology

Maturation signatures of conventional dendritic cell subtypes in COVID-19 reflect direct viral sensing

L. Marongiu, G. Protti, F. A. Facchini, M. Valache, F. Mingozzi, V. Ranzani, A. R. Putignano, L. Salviati, V. Bevilacqua, S. Curti, M. Crosti, M. D'Angio, L. R. Bettini, A. Biondi, L. Nespoli, , F. Granucci

This study identifies maturation signatures of conventional dendritic cell subtypes in COVID-19, showing that cDC2s exhibit viral sensing and inflammatory activation while losing antigen presentation capacity, correlating with disease severity.

bioRxiv · Mar 3, 2021Immunology

The physical form of microbial ligands bypasses the need for dendritic cell migration to stimulate adaptive immunity

F. Borriello, R. Spreafico, V. Poli, J. Chou, N. Barrett, L. Lacanfora, M. Franco, L. Marongiu, Y. Iwakura, F. Pucci, M. Kruppa, Z. Ma, D. Williams, I. Zanoni

This study shows that soluble fungal polysaccharides are immunosilent in peripheral tissues but become potent immunogens in draining lymph nodes without requiring dendritic cell migration.

bioRxiv · Mar 3, 2020 · PreprintImmunology