Author

F. J. Zapatero-Belinchon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:diffusion model· 1

Frequent Co-Authors

G. Gerold· 2 shared A. Gastia-Sastre· 1 shared A. Li· 1 shared A. Pich· 1 shared A. Richter· 1 shared A. Rodriguez-Hernandez· 1 shared A. Viejo-Borbolla· 1 shared B. K. Shoichet· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

G. Gerold

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiophysicsbioRxivPreprintJan 12, 2023

Structure-based discovery of inhibitors of the SARS-CoV-2 Nsp14 N7-methyltransferase

I. Singh, F. Li, E. Fink…·B. K. Shoichet

The paper identifies multiple inhibitors of SARS-CoV-2 Nsp14 N7-methyltransferase using docking strategies, with some showing sub-10 M potency and selectivity.

DOI 10.1101/2023.01.12.523677

virusprotein structure

𝕏 PostBluesky

MicrobiologybioRxivNov 18, 2022

Innate immune response to SARS-1 CoV-2 infection contributes to neuronal damage in human iPSC-derived peripheral neurons

V. Passos, L. M. Henkel, J. Wang…·A. Viejo-Borbolla

This study infects human iPSC-derived CNS and PNS neurons with SARS-CoV-2 and finds that PNS neurons experience more severe neurodegeneration linked to innate immune activation.

DOI 10.1002/jmv.29455

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintSep 22, 2022

Pharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonism

B. Mhlekude, D. Postmus, J. Weiner…·C. Goffinet

This study shows JQ-1 inhibits SARS-CoV-2 replication via NRF-2 activation but is counteracted by viral antagonism, leading to transient antiviral effects.

DOI 10.1101/2022.09.22.508962

humanbulk RNA-seq

𝕏 PostBluesky