Author

J. Weiner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 2 Microbiology· 2 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:ecology & biodiversity· 2

Frequent Co-Authors

P. Moura-Alves· 2 shared S. H. E. Kaufmann· 2 shared T. Domaszewska· 2 shared A. A. Kuehl· 1 shared A. Jacinto· 1 shared A. Kreuchwig· 1 shared A. Pich· 1 shared A. Richter· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

P. Moura-Alves

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Osteopontin in colitis-associated carcinoma

S. Manna, M. Sehn, D. Cardoso da Silva, J. J. Wiese, C. Heldt, I. Plumbom, T. Conrad, C. C. Husemann, K. Kleo, L. Derezanin, V. Dony, S. K. Farahani, F. Weiss, A. A. Kuehl, S. Schallenberg, , M. Schumann

This study investigates the role of osteopontin (SPP1/OPN) in colitis-associated carcinoma (CAC) using a multi-omics approach, revealing its indirect immunosuppressive role in the tumor microenvironment.

bioRxiv · Dec 15, 2023 · PreprintCancer Biology

Pharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonism

B. Mhlekude, D. Postmus, J. Weiner, S. Stenzel, F. J. Zapatero-Belinchon, R. Olmer, J. Jansen, A. Richter, J. Heinze, N. Heinemann, B. Muhlemann, S. Schroeder, T. C. Jones, M. A. Muller, C. Drosten, , C. Goffinet

This study shows JQ-1 inhibits SARS-CoV-2 replication via NRF-2 activation but is counteracted by viral antagonism, leading to transient antiviral effects.

bioRxiv · Sep 22, 2022 · PreprintMicrobiology

The need for alternative plant species interaction models

C. Damgaard, J. Weiner

The paper modifies classical Lotka-Volterra models to address limitations in plant species interaction analysis and evaluates their performance using Bayesian modeling on field data.

bioRxiv · Nov 8, 2020Ecology

Effects of kin recognition on root traits of wheat germplasm over 100 years of breeding

L. P. Kiaer, J. Weiner, C. R. Rasmussen

This study investigates kin recognition in wheat germplasm over 100 years of breeding, finding that root traits respond differently to substrates from related versus unrelated genotypes.

bioRxiv · Sep 4, 2020 · PreprintPlant Biology

Does metal pollution affect stoichiometry of soil-litter food webs?

M. Asselman, L. Sobczyk, J. Weiner, S. Scheu, A. Rozen

The paper examines how metal pollution affects elemental ratios in a terrestrial detritivorous food web across six sites with varying metal contamination levels.

bioRxiv · Dec 17, 2019Ecology

Inhibition of host Lactate dehydrogenase A by a small-molecule limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid

G. Krishnamoorthy, P. Kaiser, U. Abu Abed, J. Weiner, P. Moura-Alves, V. Brinkmann, S. H. E. Kaufmann

This paper shows that inhibiting host LDHA with FX11 limits M. tuberculosis growth and enhances the effectiveness of isoniazid in a mouse model of TB.

bioRxiv · May 7, 2019 · PreprintMicrobiology

Analysis of immunological resistance to primary Mycobacterium tuberculosis infection in humans

J. Weiner, T. Domaszewska, S. Donkor, P. Hill, J. Sutherland

The paper identifies gene expression and antibody signatures associated with resistance to Mycobacterium tuberculosis infection in humans.

bioRxiv · Feb 15, 2019 · PreprintImmunology

The Aryl Hydrocarbon Receptor senses the Henna pigment Lawsone and mediates Yin-Yang effects on skin homeostasis

L. Lozza, P. Moura-Alves, T. Domaszewska, C. Lage Crespo, I. Streata, A. Kreuchwig, M. Bechtle, M. Klemm, U. Zedler, S. Ungureanu Bogdan, U. Guhlich-Bornhof, A.-B. Koehler, M. Staeber, H.-J. Mollenkopf, R. Hurwitz, , S. H. E. Kaufmann

This study shows that Lawsone, a Henna pigment, activates the AhR receptor in skin cells, with both beneficial and harmful effects depending on the physiological context.

bioRxiv · Nov 4, 2018 · PreprintCell Biology