A CRISPR activation screen identifies FBXO22 as an E3 ligase supporting targeted protein degradation
A. A. Basu, C. Zhang, I. A. Riha, A. Magassa, F. Ko, X. Zhang
This study identifies FBXO22 as an E3 ligase that supports ligand-induced protein degradation through PROTACs, expanding the toolkit for targeted protein degradation.
bioRxiv · Sep 15, 2023 · PreprintBiochemistry