Author

R. De Gasperi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. P. Cardozo· 3 shared A. Aslan· 2 shared C. A. Toro· 2 shared M. Brotto· 2 shared W. Zhao· 2 shared X.-H. Liu· 2 shared Z. A. Graham· 2 shared A. M. Raczkowski· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersPhysiology

C. P. Cardozo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Muscle-restricted Nox4 knockout partially corrects muscle contractility following spinal cord injury in mice

C. A. Toro, R. De Gasperi, A. Aslan, N. Johnson, M. M. Siddiq, C. Chow, W. Zhao, L. Harlow, Z. A. Graham, X.-H. Liu, J. Sadoshima, R. Iyengar, C. P. Cardozo

This study shows that muscle-specific Nox4 knockout in mice improves muscle contractility after spinal cord injury, though force remains lower than in uninjured controls.

bioRxiv · Aug 4, 2023 · PreprintPhysiology

Septin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function.

R. De Gasperi, L. Csernoch, B. Dienes, M. Gonczi, J. K. Chakrabarty, S. Goeta, A. Aslan, C. A. Toro, D. Karasik, L. M. Brown, M. Brotto, C. P. Cardozo

The paper identifies Septin 7 as a Numb binding partner that helps maintain sarcomere structure and muscle function in aging skeletal muscle.

bioRxiv · May 11, 2023Physiology

Numb is required for optimal contraction of skeletal muscle

R. De Gasperi, C. Mo, D. Azulai, Z. Wang, L. M. Harlow, Y. Du, Z. A. Graham, X.-h. Liu, L. Guo, B. Zhang, F. Ko, A. M. Raczkowski, W. A. Bauman, W. Zhao, M. Brotto, C. P. Cardozo

This study shows that Numb is essential for skeletal muscle function, as its knockout reduces force, alters mitochondrial structure, and affects calcium dynamics in mice.

Journal of Cachexia, Sarcopenia and Muscle · Jan 9, 2022Peer-reviewedPhysiology