Numb is required for optimal contraction of skeletal muscle
R. De Gasperi, C. Mo, D. Azulai, Z. Wang, L. M. Harlow, Y. Du, Z. A. Graham, X.-h. Liu, L. Guo, B. Zhang, F. Ko, A. M. Raczkowski, W. A. Bauman, W. Zhao, M. Brotto, C. P. Cardozo
This study shows that Numb is essential for skeletal muscle function, as its knockout reduces force, alters mitochondrial structure, and affects calcium dynamics in mice.
Journal of Cachexia, Sarcopenia and Muscle · Jan 9, 2022Peer-reviewedPhysiology