Author

F. La Manna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. Kruithof-de Julio· 3 shared G. N. Thalmann· 2 shared I. Klima· 2 shared M. De Menna· 2 shared M. Kiener· 2 shared S. Karkampouna· 2 shared A. Califano· 1 shared A. Garofoli· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

M. Kruithof-de Julio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bladder cancer organoids as a functional system to model different disease stages and therapy response

M. Minoli, T. Cantore, M. Kiener, T. Fedrizzi, F. La Manna, S. Karkampouna, V. Genitisch, A. Rodriguez, I. Klima, P. Gasperini, B. Kiss, R. Seiler-Blarer, F. Demichelis, G. N. Thalmann, M. Kruithof-de Julio

This study uses bladder cancer patient-derived organoids to model disease stages and therapy response, identifying markers of resistance and sensitivity.

bioRxiv · Mar 31, 2022 · PreprintCancer Biology

Network-based identification and pharmacological targeting of host cell master regulators induced by SARS-CoV-2 infection

P. Laise, M. L. Stanifer, G. Bosker, X. Sun, S. Triana, P. Doldan, F. La Manna, M. De Menna, R. B. Realubit, S. Pampou, C. Karan, T. Alexandrov, M. Kruithof-de Julio, A. Califano, S. Boulant, M. J. Alvarez

This study identifies host cell master regulators affected by SARS-CoV-2 and develops a method to find drugs that reverse their inactivation without harming beneficial immune responses.

bioRxiv · Jul 3, 2021Microbiology

Patient-derived xenografts and organoids model therapy response in prostate cancer

S. Karkampouna, F. La Manna, M. R. De Filippo, M. Kiener, M. De Menna, E. Zoni, J. Grosjean, I. Klima, A. Garofoli, M. Bolis, J.-P. Theurillat, V. Genitsch, D. Keller, T. Booij, C. Stirnimann, , M. Kruithof-de Julio

This study develops a patient-derived xenograft (PDX) model of prostate cancer that mimics disease stages and identifies drug sensitivities in metastatic cases.

Nature Communications · Feb 18, 2021Peer-reviewedCancer Biology