Lipids are the preferred substrate of the protist Naegleria gruberi, relative of a human brain pathogen
M. Bexkens, V. Zimorski, M. J. Sarink, H. Wienk, J. F. Brouwers, J. F. De Jonckheere, W. F. Martin, F. R. Opperdoes, J. J. van Hellemond, A. G. M. Tielens
This study shows that Naegleria gruberi relies on lipid oxidation for growth and energy metabolism, unlike glucose or amino acids, and suggests similar metabolism in its pathogenic relative N. fowleri.
bioRxiv · Jul 24, 2018Biochemistry