F. Sessa

IL-1α secreted by subcapsular sinus macrophages promotes melanoma metastasis in the sentinel lymph node by upregulating STAT3 signaling in the tumor.

This study shows that IL-1α from subcapsular sinus macrophages promotes melanoma metastasis by enhancing STAT3 signaling in tumor cells, and blocking this pathway reduces metastasis.

A polyphenol-rich extract of Olive Mill Wastewater Enhances cancer chemotherapy effects while mitigating cardiac toxicity.

This paper shows that a polyphenol-rich extract from olive mill wastewater enhances chemotherapy effectiveness against prostate cancer while reducing cardiac toxicity in both in vivo and in vitro models.