Improving drug discovery using image-based multiparametric analysis of epigenetic landscape.
C. Farhy, S. Hariharan, J. Ylanko, L. Orozco, F.-Y. Zeng, I. Pass, F. Ugarte, C. Forsberg, C.-T. Huang, D. Andrews, A. Terskikh
This paper introduces MIEL, an image-based method for epigenetic drug screening, showing it can detect active compounds, classify functions, and predict novel drug effects with higher resolution than traditional methods.
bioRxiv · May 15, 2019Cell Biology