Author

C. Farhy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Terskikh· 3 shared C.-T. Huang· 3 shared C. Forsberg· 2 shared D. Andrews· 2 shared F. Ugarte· 2 shared J. Ylanko· 2 shared S. Hariharan· 2 shared A. Amador-Arjona· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

A. Terskikh

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Author profile →

3 papers

Recent·Most cited

Canonical BMP2/4 signaling degrades SOX2 in glioblastoma propagating cells.

F. Comadamore, A. Amador-Arjona, C. Farhy, C.-T. Huang, H. Kornblum, A. Terskikh

This study shows BMP2/4 induces SOX2 degradation in glioblastoma propagating cells, leading to differentiation into glial cells and reduced proliferation.

bioRxiv · Feb 3, 2022 · PreprintCancer Biology

Improving drug discovery using image-based multiparametric analysis of epigenetic landscape.

C. Farhy, S. Hariharan, J. Ylanko, L. Orozco, F.-Y. Zeng, I. Pass, F. Ugarte, C. Forsberg, C.-T. Huang, D. Andrews, A. Terskikh

This paper introduces MIEL, an image-based method for epigenetic drug screening, showing it can detect active compounds, classify functions, and predict novel drug effects with higher resolution than traditional methods.

bioRxiv · May 15, 2019Cell Biology

Multiparametric Signature of Glioblastoma Differentiation Revealed by Imaging of Cellular Epigenetic Landscapes

C. Farhy, S. Hariharan, J. Ylanko, L. van Woudenberg, F. Cimadamore, F. Ugarte, C. Forsberg, C.-T. Huang, D. Andrews, A. Terskikh

The paper develops MIEL, an imaging method to identify epigenetic signatures of differentiated glioblastoma cells and validates its use in selecting small molecules that induce tumor-propagating cell differentiation.

bioRxiv · Aug 16, 2018 · PreprintCancer Biology