F. W. Stearns

Scaling the fitness effects of mutations with respect to differentially adapted Arabidopsis thaliana accessions under natural conditions

The paper assesses mutation fitness effects in two Arabidopsis thaliana ecotypes under natural conditions and finds beneficial mutations accumulate, with the poorly adapted ecotype showing higher mutation variance.

Collateral fitness effects of mutations

This study identifies collateral fitness effects of mutations in E. coli, showing that 42% of missense mutations in TEM-1 β-lactamase are deleterious through mechanisms unrelated to protein function.