Author

F. Zoulim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. Testoni· 2 shared A. Blair· 1 shared A. Di Bernardo· 1 shared A. Fautrel· 1 shared A. Grubenmann· 1 shared A. Lankenau· 1 shared A. P. Bubie· 1 shared A. SALVETTI· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

B. Testoni

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Replication-driven HBV cccDNA loss in chimeric mice with humanized livers

B.-H. Zhang, Y. Zhou, B. Tempel, H. Pan, S. Horrigan, L. Luckenbaugh, F. Zoulim, J. Hu, Y.-Y. Zhang

This study shows that replication-driven cccDNA loss occurs in HBV-infected chimeric mice with humanized livers, and blocking cccDNA replenishment pathways significantly reduces cccDNA levels.

bioRxiv · Dec 28, 2023Microbiology

Hepatocellular carcinoma hosts immature neurons and cholinergic tumors that correlate with adverse molecular features and outcomes

C. A. Hernandez, C. Verzeroli, I. Chicherova, A.-J. Farca-Luna, L. Tonon, P. Bellaud, B. Turlin, A. Fautrel, Z. Macek-Jilkova, T. Decaens, S. Rebouissou, A. Viari, F. Zoulim, R. Parent

This study identifies neural features in hepatocellular carcinoma, showing cholinergic tumors correlate with adverse molecular traits and worse outcomes.

bioRxiv · Jun 14, 2022 · PreprintCancer Biology

Performance of the cobas(R) HBV RNA Automated Investigational Assay for the Detection and Quantification of Circulating HBV RNA in Chronic HBV Patients

C. SCHOLTES, A. T. Hamilton, M.-L. Plissonnier, C. Charre, B. Scott, L. Wang, F. Berby, J. French, B. Testoni, A. Blair, M. Subic, M. Hoppler, A. Lankenau, A. Grubenmann, M. Levrero, , F. Zoulim

This study evaluates the cobas(R) HBV RNA assay's performance in detecting and quantifying circulating HBV RNA in chronic HBV patients, showing high sensitivity and minimal interference from HBV DNA.

bioRxiv · Mar 9, 2022Microbiology

Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production

H. Chabrolles, H. Auclair, S. Vegna, T. Lahlali, C. Pons, M. Michelet, Y. Coute, L. Belmudes, Y. Kim, A. Di Bernardo, P. Jalaguier, M. Rivoire, L. D. Arnold, U. Lopatin, C. Combet, , A. SALVETTI

This study identifies SRSF10 as a host RNA-binding protein that restricts HBV RNA production by interacting with the HBV core protein in the nucleus of infected hepatocytes.

PLOS Pathogens · Nov 12, 2020Peer-reviewedMicrobiology

Landscape of oncoviral genotype and co-infection via Human papilloma andHepatitis B viral tumor in-situ profiling

A. P. Bubie, F. Zoulim, B. Testoni, B. Miles, M. Posner, A. Villanueva, B. Losic

The paper develops a tool to analyze viral genotypes and co-infections in tumors, finding that viral genotype and co-infection significantly impact patient survival and tumor biology.

bioRxiv · Mar 24, 2020Cancer Biology