Author

F.-x. Yu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

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Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Y. Wang· 3 shared C. He· 2 shared F. Lan· 2 shared J. Li· 2 shared Y. Gu· 2 shared C. Fang· 1 shared H. Gan· 1 shared J. Hu· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCancer Biology

Y. Wang

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Author profile →

3 papers

Recent·Most cited

TERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis

P. Yu, N. Qu, R. Zhu, J. Hu, P. Han, L. Tan, H. Gan, C. He, C. Fang, Y. Lei, J. Li, C. He, F. Lan, X. Shi, W. Wei, , Y.-l. Wang

This study shows TERT promotes thyroid cancer dedifferentiation and progression by enhancing ribosome biogenesis, and inhibiting rRNA synthesis can reverse this process.

bioRxiv · Jan 29, 2023Cancer Biology

Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a potential therapeutic target in YAP/TAZ-active cancers

Y. Gu, Y. Wang, Z. Sha, C. He, F. Lan, F.-x. Yu

bioRxiv · Feb 28, 2022Cancer Biology

HIV protease inhibitor Nelfinavir targets human DDI2 and potentiates proteasome inhibitor-based chemotherapy

Y. Gu, X. Wang, Y. Wang, J. Li, F.-x. Yu

This study shows that Nelfinavir inhibits DDI2, blocking NFE2L1 proteolysis and enhancing the effectiveness of proteasome inhibitors in cancer treatment.

bioRxiv · May 3, 2020 · PreprintCancer Biology