Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators
Nicola Masala, Manuel Mittag, Eleonora Ambrad Giovannetti, Darik A. O’Neil, Fabian J Distler, Peter Rupprecht, Fritjof Helmchen, Rafael Yuste, Martin Fuhrmann, Heinz Beck, Michael Wenzel, Tony Kelly
The paper reports that common AAV transduction procedures can induce artefactual Ca2+ micro-waves in the hippocampus and provides an alternative method to avoid this issue.
eLife · Jul 23, 2024Peer-reviewedNeuroscience