Migratory dermal gamma delta T cells determine the balance between lung immunity and tissue damage during Nippostrongylus brasiliensis infection
Pedro Henrique Papotto, James E Parkinson, Brian H. K. Chan, I‐Hsuan Lin, Georgia E. Baldwin, Faith Denny, Lili Zhang, Rebecca J. Dodd, Stella T. Pearson, Natalie Fischhaber, Joanne Elizabeth Konkel, David R. Withers, Matthew R. Hepworth, Judith E. Allen
This study shows that dermal gamma delta T cells migrate from the skin to the lungs during Nippostrongylus brasiliensis infection, balancing IL-17 and IFN-gamma responses to prevent lung damage.
bioRxiv · Jan 7, 2025 · PreprintImmunology