Rebecca J. Dodd

This study shows that covalent attachment of heavy chains to hyaluronan protects it from ROS-induced fragmentation during inflammation.

The paper uses imaging mass cytometry to analyze ECM composition in mouse models of allergic airway inflammation, identifying distinct matrix environments associated with different cell types and tissue regions.

This study shows that blocking CD44, a hyaluronan receptor, reduces inflammation and improves survival in mice infected with SARS-CoV-2.

This paper investigates how PTX3's quaternary structure enables HA crosslinking via interactions with HC1, revealing pH-dependent binding and structural flexibility.

This study shows that dermal gamma delta T cells migrate from the skin to the lungs during Nippostrongylus brasiliensis infection, balancing IL-17 and IFN-gamma responses to prevent lung damage.

This study chemically modifies HA oligosaccharides to differentially modulate their binding to HABPs, revealing structural insights into HA-receptor interactions.